Yale / Engineering

Biomolecular Engineering: Engineering of Immunity

By Mark Saltzman | Introduction to Biomedical Engineering Lecture 9 of 25

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Lecture Description

Professor Saltzman talks about the importance of vaccines, and particularly the role of bioengineering in vaccine development. He first addresses the question of "what is a vaccine" and the role of the immune system. He then describes the biological basis, symptoms, and history of smallpox as a devastating disease worldwide, and how--starting with the work of Edward Jenner--an effective vaccine was systematically developed from cow lesions. Next, methods to deliver vaccine to a wide population are introduced. Finally, Professor Saltzman touches on the possible reemergence of smallpox as weapon for bioterrorism.

Course Description

The course covers basic concepts of biomedical engineering and their connection with the spectrum of human activity. It serves as an introduction to the fundamental science and engineering on which biomedical engineering is based. Case studies of drugs and medical products illustrate the product development-product testing cycle, patent protection, and FDA approval. It is designed for science and non-science majors.

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Lecture Transcript and Reading Assignment

Course Index

  1. What Is Biomedical Engineering?
  2. What Is Biomedical Engineering? (cont)
  3. Genetic Engineering
  4. Genetic Engineering (cont)
  5. Cell Culture Engineering
  6. Cell Culture Engineering (cont)
  7. Cell Communication and Immunology
  8. Cell Communication and Immunology (cont)
  9. Biomolecular Engineering: Engineering of Immunity
  10. Biomolecular Engineering: Engineering of Immunity (cont)
  11. Biomolecular Engineering: General Concepts
  12. Biomolecular Engineering: General Concepts (cont)
  13. Cardiovascular Physiology
  14. Cardiovascular Physiology (cont)
  15. Cardiovascular Physiology (cont)
  16. Renal Physiology
  17. Renal Physiology (cont)
  18. Biomechanics and Orthopedics
  19. Biomechanics and Orthopedics (cont)
  20. Bioimaging
  21. Bioimaging (cont)
  22. Tissue Engineering
  23. Tissue Engineering (cont)
  24. Biomedical Engineers and Cancer
  25. Biomedical Engineers and Artificial Organs
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